Potential new cure found for baldness, say researchers

Potential new cure found for baldness, say researchers

Potential new cure found for baldness, say researchers

The new cure uses another drug, Way-316606, that was created to inhibit SFRP1 as treatment for osteoporosis.

According to researchers from The University of Manchester's Centre for Dermatology Research, a new drug - originally created to treat osteoporosis - could help men and women suffering from baldness.

One of the researchers on the project Nathan Hawkshaw said the next step for the drug would be for a clinical trial to find out whether WAY-316606 is safe.

Finasteride only works for men and like minoxidil, it has side effects, is not available on the NHS and doesn't always work.

There are now two types of drugs aimed at treating male pattern baldness, minoxidil and finasteride, but neither are available on the NHS, and neither promise drastic results. They found that CsA changed how the follicles expressed a protein called SFRP1, which stunts the development and growth of hair follicles and other tissues in the body. But don't get too excited: Although the study authors concluded that WAY-316606 has the "potential to treat human hair loss disorders", it has only been tested on hair samples - not on actual, living humans.

The study was published Tuesday in the open access journal PLOS Biology.

The drug, known as Cyclosporine A (CsA), has been in medical use since 1983 in the form of eye drops, to prevent rejection of organ transplants, treating of rheumatoid arthritis and osteoporosis, etc.

If this could be developed into an effective treatment, then it could have a significant impact on those suffering from hair loss, which for many can cause psychological and mental distress.

The drug targets so-called Janus kinase (JAK) enzymes, which cause dormant hair follicles, and it promoted a 92% improvement in hair growth.

However, CaA's severe side effects other than a boost in hair growth make it an unappealing choice.

The lack of treatment for the hereditary condition has led to thousands of men undergo painful hair transplant procedures.

"That said, more research will need to be done before it can be used by people with hair loss", he adds, saying that treatments for baldness are often hit and miss.

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