Ibuprofen Linked to Men's Fertility Problems

Ibuprofen Linked to Men's Fertility Problems

Ibuprofen Linked to Men's Fertility Problems

Researchers even tested ibuprofen on "bits of human testes" collected from organ donors and saw the same result: The drug hampered testosterone output.

The study looked at a small group of men - only 31 - ages 18-35 over six weeks.

In addition to producing sperm, testicles secrete testosterone, the primary male hormone.

'In the men, luteinizing hormone (LH) and ibuprofen plasma levels were positively correlated, and the testosterone/LH ratio decreased.

"This repression results in the elevation of the stimulatory pituitary hormones, resulting in a state of compensated hypogonadism, a disorder associated with adverse reproductive and physical health disorders".

Richard Quinton, MD, from Newcastle University in England and the Society for Endocrinology, says: "This is a landmark study that elegantly combines clinical and basic research, at both tissue and cellular levels, to show that ibuprofen, a common over-the-counter painkiller, can reversibly hinder testosterone production by testicular cells".

The detrimental effects of daily ibuprofen were almost immediate. Men were then divided - 14 in an ibuprofen group, 17 in a placebo group.

Men who take high doses of ibuprofen for months at a time may be at greater risk of fertility issues and also other health problems, such as muscle wastage, erectile dysfunction and fatigue, scientists have found.

The drugs are considered "anti-androgenic", which means they lower the amount of hormones present in males.

HollywoodLifers, did you know the negative effects of ibuprofen?

However, for men, it could compromise their ability to procreate, a new study suggests. Inhibition of testosterone levels was found to be significant and dose-dependent after 24 and 48 hours of ibuprofen exposure (in doses which corresponded to the oral doses used in the trial).

The study isn't the first to suggest that ibuprofen could be causing more harm than good.

If you are concerned about your levels of testosterone and your ibuprofen use, though, it's worth chatting to your GP so you can get checked out and find a way to deal with chronic aches and pains in a healthy way.

The hormonal imbalance caused compensated hypogonadism, which is a condition linked to decreased male fertility, depression, and an increased risk of heart attack or stroke.

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