Pochettino expects Spurs to thrive without Kane
Spurs team-mate Jan Vertonghen hailed his side's good fortune as they continue to pressurise the leaders and look to cement Champions League football for next season.
Like Pochettino's Tottenham, Southampton are a club with a clear philosophy.
Spurs cut Chelsea's lead at the top of the table to 10 points with their latest win at White Hart Lane and Pochettino was delighted to see his side cope without their talisman.
Other hand, Southampton have also 3 wins in last 5 league encounter but rest 2 games of them were defeats.
Spurs came closest to adding another goal as substitute Vincent Janssen led a counterattack and forced another good save from Forster.
With the build-up well underway ahead of Sunday's clash, we have analysed the THREE key battles which will go someway to deciding the outcome at White Hart Lane...
Kyle Walker is a doubt for Tottenham Hotspur's match against Southampton on Sunday after twisting his ankle following an accident at home.
Winks was straight into the action with a trademark run before winning Spurs a free-kick in a good position.
James Ward-Prowse pulled a goal back for the visitors but it wasn't enough to stop Spurs from taking the three points. "I'm very pleased with his performance".
They are unbeaten in their opening 14 home top-flight league games of a season for the first time since 1964-65.
Manager Claude Puel's side now occupy 10th place with 33 points, with the likely goal for the rest of the season being to finish as high as possible on the table with nothing left to play for.
Southampton emerged after the break with greater attacking intent and was rewarded seven minutes into the second half. Mitchell, who resigned in August and is now on gardening leave, was the driving force behind the signing of Nkoudou, who is hardly rated by Pochettino; evidently, Saints' success in replacing their players was about more than one man.
Fourteen of those goals have come in the league - four more than he achieved last season. He had won it and he converted it. Alli now has 17 goals in all competitions this season. Out of those 9 meetings, the two teams made sure to score at least one goal in the match.
Alli signed for Spurs in 2015 from MK Dons, signing a five-and-a-half year deal.